Summit, Colorado Center for Personalized Medicine to Develop Saliva Tests for COVID, Head & Neck Cancer

AURORA, Colo., Oct. 14, 2020 /PRNewswire/ — Summit Biolabs, Inc., an early-stage molecular diagnostics company specializing in saliva-based testing for COVID-19 and head & neck cancer, and the Colorado Center for Personalized Medicine (CCPM) at the University of Colorado Anschutz Medical Campus announced today a broad strategic collaboration involving research, development and commercialization of saliva liquid-biopsy tests for early cancer detection and diagnosis of COVID-19 and other viral contagions.

The CCPM holds one of the largest research biobanks in the United States with clinical data from more than 8.7 million de-identified patient records and plans to integrate the data with personalized genomic information.

“This partnership brings two innovative programs together to optimize COVID testing at a time when it’s desperately needed,” says Kathleen Barnes, Ph.D., Professor and Director of CCPM at the University of Colorado Anschutz Medical Campus. “Collaborations like this are crucial in moving research forward and advancing and expanding clinical testing to as many members of our community as possible. Working with Summit Biolabs, and leveraging technology developed by our colleagues here at the Anschutz Medical Campus, will help us achieve these goals and establish a non-invasive testing process that will benefit patients in Colorado and beyond.”

Summit Biolabs is developing breakthrough tests to improve the detection of COVID-19 and to advance the early detection of human cancers, including head & neck cancer, using simple, non-invasive saliva liquid-biopsy technology developed by Dr. Shi-Long Lu and colleagues at the University of Colorado Anschutz Medical Campus. Head & neck cancer has been scientifically overlooked, yet is medically important. Summit Biolabs’ research foundation and competency in head & neck cancer diagnosis enabled the company’s pivot to saliva-based testing for coronavirus, COVID-19.

“We are excited to collaborate with CCPM to develop and commercialize Summit Biolabs’ portfolio of developmental saliva or non-blood liquid-biopsy tests.” said Bob Blomquist, Chief Executive Officer at Summit Biolabs. “This collaboration broadens and strengthens Summit Biolabs’ ability to bring to market life-changing saliva liquid-biopsy tests that ultimately enable better treatment and improved outcomes for patients.”

About Summit Biolabs

Summit Biolabs is harnessing the power of saliva-based diagnostics to address critical challenges in COVID-19 and head & neck cancer testing. Founded on the discoveries of Dr. Shi-Long Lu, Associate Professor of Otolaryngology, Summit Biolabs is being spun out from the University of Colorado Anschutz Medical Campus.

Summit Biolabs is pioneering early detection of head & neck cancer recurrence using a first of its kind saliva liquid-biopsy test, HNKlear. HNKlear is a proprietary, non-invasive saliva test that provides more effective, more accurate, and earlier detection of head and neck cancer recurrence than traditional diagnostic methods. Summit Biolabs is leveraging its core competencies in saliva-based molecular diagnostics and viral nucleic acid testing (i.e., oral oncogenic human papillomavirus detection) to diagnose COVID-19. Along with our clinical and laboratory partners, Summit Biolabs is developing the first comprehensive panel of highly-accurate saliva-based tests for COVID-19 infection, quantitation, and immune response. Summit Biolabs is headquartered in Aurora, Colorado.

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China carries out 4.2 million tests in Qingdao

BEIJING — China says it has carried out more than 4.2 million tests in the northern port city of Qingdao, with no new cases of coronavirus found among the almost 2 million sets of results received.

The city has reported a total of 12 cases, six with symptoms and six without, since the new outbreak was first spotted over the weekend at a hospital.

China on Wednesday reported 27 new cases of coronavirus, including 13 new cases of local transmission and 14 cases brought from outside the country. The local cases included seven that had been shifted to confirmed from asymptomatic. It wasn’t immediately clear whether any of those involved cases reported in Qingdao.

China has reported a total of 4,634 deaths among 85,611 confirmed cases of COVID-19.


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HERE’S WHAT YOU NEED TO KNOW ABOUT THE VIRUS OUTBREAK:

— WHO: Europe reported more than 700,000 coronavirus cases last week

— Dutch order bars, restaurants closed over coronavirus concerns

— India has 55,342 coronavirus cases, lowest single-day tally since mid-August

— Safety monitoring panel will try to determine what might have caused sickness in a second COVID-19 vaccine trial paused over unexplained illness

— New poll finds coronavirus pandemic has thrust many Americans into role of caring for an older or disabled loved one for first time.

— Cristiano Ronaldo latest high-profile soccer player infected with the coronavirus, Portuguese soccer federation says.

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— Follow AP’s pandemic coverage at http://apnews.com/VirusOutbreak and https://apnews.com/UnderstandingtheOutbreak

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HERE’S WHAT ELSE IS HAPPENING:

BOISE, Idaho — Idaho health care experts say coronavirus is increasing as kids are returning to school — but most of the new infections aren’t happening in school buildings.

Instead, Dr. Joshua Kern with St. Luke’s hospitals in the Magic Valley says it’s likely because many people are treating the return to school like a return to normalcy and slacking off on good habits like social distancing, hand-washing and mask-wearing.

A tally from Johns Hopkins University shows Idaho currently ranks sixth in the country for new cases per capita, with a total of more than 48,660 confirmed cases of coronavirus statewide. So far more than 500 Idaho residents have died of COVID-19.

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DENVER — Colorado is experiencing another surge of coronavirus cases and hospitalizations, prompting Gov. Jared Polis to plead Tuesday with residents to wear masks, stay home as much as possible, and maintain social distancing practices.

As of Tuesday, Colorado’s three-day average positivity rate — the percentage of total tests coming in positive — was 5.4%, and the state recorded 1,000 new cases both on Saturday and on Monday, the highest daily numbers recorded during the pandemic, Polis said.

About 290 people were hospitalized for COVID-19 on Tuesday, the highest total since May 31, The Denver Post reported.

During a briefing on the pandemic, Polis didn’t suggest he was contemplating renewed mandatory restrictions on business or other activities to stem the surge. But he insisted: “If this continues, our hospital capacity will be in jeopardy.”

The World Health Organization recommends

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China Tests Entire City For Virus As Europe Tightens Controls

China rushed Tuesday to test an entire city of nine million people within days after a minor coronavirus outbreak in the sprawling country, a far cry from the struggle in Europe to tackle surging infections with tough new steps including partial lockdowns.

The virus is still spreading rapidly worldwide, with over one million deaths and 37 million infections, and many nations that suppressed their first outbreaks now face a second wave.

Without a vaccine, governments are wary of allowing the virus to spread unchecked.

More than four million samples had been collected as of Tuesday in the Chinese city of Qingdao More than four million samples had been collected as of Tuesday in the Chinese city of Qingdao Photo: AFP / STR

China — where Covid-19 first emerged late last year — launched a drive to test all residents of Qingdao after a handful of cases were detected on Sunday.

More than four million samples had been collected and 1.9 million results returned as of Tuesday afternoon, Qingdao authorities said, adding that no new cases had been found beyond already confirmed infections.

Chinese officials intend to test the entire city — around 9.4 million people — by Thursday.

Britain's Prime Minister Boris Johnson has ordered pubs to close early to help stem the virus spread Britain’s Prime Minister Boris Johnson has ordered pubs to close early to help stem the virus spread Photo: AFP / JUSTIN TALLIS

In scenes contrasting with the fumbled testing efforts elsewhere, health workers in protective clothing swiftly set up tents and residents queued deep into Monday night to provide samples.

In Europe, governments are battling to curb surges with new controls and increased testing, while trying to avoid the devastating nationwide lockdowns of March and April.

Dutch Prime Minister Mark Rutte announced the Netherlands will go into “partial lockdown” from 2000 GMT on Wednesday, with all bars, caf?s and restaurants to close for two weeks at least.

French President Emmanuel Macron is expected to announce tighter restrictions and faster testing in a prime-time TV interview Wednesday night, with some media speculating Paris and other cities could face evening curfews.

Map with number of Covid-19 deaths by country as of October 13 at 1100 GMT Map with number of Covid-19 deaths by country as of October 13 at 1100 GMT Photo: AFP / Simon MALFATTO

Hospitals in Paris will have most of their intensive care beds packed with Covid-19 patients as soon as next week, the system’s chief warned Tuesday.

“It’s inevitable,” Martin Hirsch, the head of the 39 hospitals in Paris and its suburbs, told the Parisien newspaper, estimating beds would reach 70-90% capacity by October 24.

Russia on Tuesday reported its highest-ever number of daily virus deaths, at 244, and a record number of new cases at almost 14,000.

With the pandemic already claiming more than one million lives worldwide, scientists in different nations are rushing to develop vaccines and effective treatments With the pandemic already claiming more than one million lives worldwide, scientists in different nations are rushing to develop vaccines and effective treatments Photo: AFP / Yasin AKGUL

Italy imposed new, tougher rules to control a resurgence, including an end to parties, amateur football matches and snacking at bars at night.

Polish Prime Minister Mateusz Morawiecki on Tuesday became the latest high-profile figure to go into quarantine after coming into contact with a person with Covid-19.

And Portugal’s football federation said star striker Cristiano

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