Health Professionals Follow-Up Study

About HPFS:

The Health Professionals Follow-Up Study (HPFS) began in 1986. The purpose of the study is to evaluate a series of hypotheses about men’s health relating nutritional factors to the incidence of serious illnesses, such as cancer, heart disease, and other vascular diseases. This all-male study is designed to complement the all-female Nurses’ Health Study, which examines similar hypotheses. The HPFS is sponsored by the Harvard School of Public Health and is funded by the National Cancer Institute. Learn More About HPFS.

Thank you, participants! In 2018, nearly 90% of participants responded to the bi-annual study questionnaire. Their commitment provides the consistent data required to make progress in the study of men’s health.

The Nutrition Source

How eating right and having an active lifestyle can benefit you. Read More to learn about healthy nutrition choices.

News and Recent Research Highlights

  • Coffee Intake and Colorectal Cancer: our study provides evidence for the benefit of coffee drinking among patients with nonmetastatic colorectal cancer. Read More
  • Mediterranean diet and cognitive function: our latest findings provide further evidence that a healthy dietary pattern may prevent or delay cognitive decline. Read More
  • Physical activity and cognitive function: being physically active during early adulthood and mid-to-late life independently contribute to prevention of poor subjective cognitive function in late-life. Read more
  • Kidney Stones: Dietary and Lifestyle Risk Factors. We estimated the proportion of kidney stones that could be prevented if individuals modified a number of lifestyle factors to minimize their risk Read More


Donations and bequests to the Friends of the Health Professionals Follow-up Study Fund help to sustain our continued work. Donations may be sent to the Harvard T.H. Chan School of Public Health. For information on how to give or to make a secure gift online, please visit and indicate that the gift is in support of the Friends of the Health Professionals Follow-Up Study Fund.

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