Meloxicam Uses, Dosage, Side Effects & Warnings

Generic Name: meloxicam (mel OKS i kam)
Brand Names: Anjeso, Mobic, Qmiiz OD, Vivlodex

Medically reviewed by Sophia Entringer, PharmD. Last updated on Jun 2, 2020.

What is meloxicam?

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

Meloxicam is used to treat pain or inflammation caused by rheumatoid arthritis and osteoarthritis in adults.

Meloxicam is also used to treat juvenile rheumatoid arthritis in children who are at least 2 years old.

The Anjeso brand of meloxicam is used to treat moderate to severe pain in adults.

Vivlodex is for use only in adults. Qmiiz is for adults and children weighing at least 132 pounds (60 kilograms).

Important information

Meloxicam can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Get emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

Meloxicam may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.

Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

Avoid smoking and drinking alcohol as they also increase your risk of stomach bleeding.

Ask a doctor or pharmacist before using any other cold, allergy, or pain medicine. Medicines similar to meloxicam are contained in many combination medicines. Check the label to see if a medicine contains an NSAID (non-steroidal anti-inflammatory drug) such as aspirin, ibuprofen, ketoprofen, or naproxen.

Meloxicam can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine.

Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Meloxicam may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.

You should not use meloxicam if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

To make sure this medicine is safe for you, tell your doctor if you have:

  • heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;

  • a history of heart attack, stroke, or blood clot;

  • a history of stomach ulcers or bleeding;

  • asthma;

  • kidney disease (or if you are on dialysis);

  • liver disease; or

  • fluid retention.

Taking meloxicam during the last 3 months of pregnancy may harm the unborn baby. Tell your

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Gabapentin: Uses, Dosage, Side Effects, Warnings

Generic Name: gabapentin (GA ba PEN tin)
Brand Names: Gralise, Horizant, Neurontin, Gabarone

Medically reviewed by Kaci Durbin, MD Last updated on Jun 7, 2020.

What is gabapentin?

Gabapentin is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

Gabapentin is used together with other medicines to treat partial seizures in adults and children at least 3 years old.

Gabapentin is also used to treat neuropathic pain (nerve pain) caused by herpes virus or shingles (herpes zoster) in adults.

Use only the brand and form of gabapentin your doctor has prescribed. Check your medicine each time you get a refill to make sure you receive the correct form.

The Gralise brand of gabapentin is indicated for the management of neuropathic pain only. It is not used for epilepsy.

Horizant is used to treat nerve pain and restless legs syndrome (RLS).

The Neurontin brand is used to treat seizures in adults and children who are at least 3 years old, in addition to neuropathic pain.

Important Information

Gabapentin can cause life-threatening breathing problems, especially in older adults or people with COPD. Seek emergency medical attention if you have very slow breathing.

Some people have thoughts about suicide or behavior changes while taking gabapentin. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Avoid driving or hazardous activity until you know how gabapentin will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Do not stop using gabapentin suddenly, even if you feel fine.

Before taking this medicine

You should not use gabapentin if you are allergic to it.

To make sure gabapentin is safe for you, tell your doctor if you have ever had:

Some people have thoughts about suicide while taking this medicine. Children taking gabapentin may have behavior changes. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Seizure control is very important during pregnancy, and having a seizure could harm both mother and baby. Do not start or stop taking gabapentin for seizures without your doctor’s advice, and tell your doctor right away if you become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How should I take gabapentin?

Take gabapentin exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take in larger or smaller amounts or for longer than recommended.

If your doctor changes your brand, strength, or type of gabapentin, your dosage needs may change. Ask your pharmacist if you have any questions about the new kind of gabapentin you receive at the pharmacy.

The Horizant brand of gabapentin should not be taken during the day.

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Amlodipine: Drug Uses, Side Effects & Dosage

Generic Name: amlodipine (am LOE di peen)
Brand Names: Katerzia, Norvasc

Medically reviewed by Sanjai Sinha, MD Last updated on Dec 1, 2019.

What is amlodipine?

Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.

Amlodipine is used to treat chest pain (angina) and other conditions caused by coronary artery disease.

Amlodipine is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Amlodipine is for use in adults and children who are at least 6 years old.

Important information

Before taking amlodipine, tell your doctor if you have congestive heart failure or liver disease.

Drinking alcohol can further lower your blood pressure and may increase certain side effects of amlodipine.

If you are being treated for high blood pressure, keep using amlodipine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Amlodipine is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Tell your doctor about all other heart or blood pressure medications you are taking.

Your chest pain may become worse when you first start taking amlodipine or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.

Before taking this medicine

You should not take amlodipine if you are allergic to it.

To make sure amlodipine is safe for you, tell your doctor if you have ever had:

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether amlodipine will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.

Amlodipine can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breast-feeding.

Amlodipine is not approved for use by anyone younger than 6 years old.

How should I take amlodipine?

Take amlodipine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

You may take amlodipine with or without food. Take the medicine at the same time each day.

Shake the Katerzia oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Your blood pressure will need to be checked often.

Your chest pain may become worse when you first start taking amlodipine or when your dose is increased. Call your doctor if your chest pain is severe or

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Tramadol : Uses, Side Effects, Dosage, Warnings

Generic Name: tramadol (TRAM a dol)
Brand Names: ConZip, Ultram, Ultram ER

Medically reviewed by Kaci Durbin, MD Last updated on Mar 1, 2020.

What is tramadol?

Tramadol is a narcotic-like pain reliever.

Tramadol is used to treat moderate to severe pain in adults.

The extended-release form of tramadol is for around-the-clock treatment of pain. The extended-release form of tramadol is not for use on an as-needed basis for pain.

Important Information

Seizures have been reported in patients taking tramadol. Your risk of seizures is higher if you are taking higher doses of tramadol over what is recommended. Seizure risk is also higher in those with a seizure disorder or those taking certain antidepressants or opioid medications.

Tramadol should not be used if you are suicidal or prone to addiction.

You should not take tramadol if you have severe breathing problems, a blockage in your stomach or intestines, or if you have recently used alcohol, sedatives, tranquilizers, narcotic medication, or an MAO inhibitor (isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others).

Tramadol can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

Tramadol should not be given to a child younger than 12 years old. Ultram ER should not be given to anyone younger than 18 years old.

Taking tramadol during pregnancy may cause life-threatening withdrawal symptoms in the newborn.

Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

Before taking this medicine

You should not take tramadol if you are allergic to it, or if you have:

  • severe asthma or breathing problems;

  • a blockage in your stomach or intestines;

  • if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or

  • if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine).

Tramadol should not be given to a child younger than 12 years old. Ultram ER should not be given to anyone younger than 18 years old.

Do not give this medicine to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Avoid giving this medicine to children between 12 to 18 years of age who have conditions that may cause breathing problems.

Seizures have occurred in some people taking tramadol. Talk with your doctor about your seizure risk, which may be higher if you have ever had:

  • a head injury, epilepsy or other seizure disorder;

  • f you also use certain antidepressants, muscle relaxants, opioids, or other medications.

If you use tramadol while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or

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Side Effects, Dosage, Uses, and More

  1. Amlodipine oral tablet is available as a brand-name drug and a generic drug. Brand name: Norvasc.
  2. Amlodipine comes only as a tablet you take by mouth.
  3. Amlodipine oral tablet is used to treat high blood pressure, coronary artery disease, and angina.

Amlodipine oral tablet may cause extreme sleepiness. It can also cause other side effects.

More common side effects

The more common side effects that can occur with amlodipine include:

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Low blood pressure. Symptoms can include:
    • severe dizziness
    • lightheadedness
    • fainting
  • More chest pain or a heart attack. When you first start taking amlodipine or increase your dosage, your chest pain may get worse or you may have a heart attack. Symptoms can include:
    • chest pain or discomfort
    • upper body discomfort
    • shortness of breath
    • breaking out in a cold sweat
    • unusual tiredness
    • nausea
    • lightheadedness

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

  • Liver problems warning: Amlodipine is processed by your liver. If your liver isn’t working well, more of this drug may stay in your body longer. This puts you at risk for more side effects. If you have severe liver problems, your doctor may give you a lower dosage.
  • Heart problems warning: If you have heart problems, such as narrowing of your arteries, this drug may increase your risk of health problems. You may have low blood pressure, worse chest pain, or a heart attack after starting or increasing your dose of amlodipine. If this happens, call your doctor or go to the emergency room right away.

Amlodipine is a prescription drug. It comes as a tablet you take by mouth.

Amlodipine is available as the brand-name drug Norvasc. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

Amlodipine may be taken in combination with other heart medications.

Why it’s used

Amlodipine is used to lower your blood pressure. It can be used alone or in combination with other heart medications.

Amlodipine is also used to help blood flow more easily to your heart when the arteries in your heart are blocked.

Amlodipine is also used to treat coronary artery disease and angina (chest pain).

How it works

Amlodipine belongs to a class of drugs called

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Caffeine Effects on Sleep Taken 0, 3, or 6 Hours before Going to Bed

INTRODUCTION

Caffeine in doses ranging from 200-400 mg have been shown to be effective and are often utilized to sustain performance in the context of sleep deprivation, sedation, and sleep restriction.17 Up to 500 mg of caffeine can be found in commercially available 16-oz servings of brewed coffee.8 The use of similarly high doses of caffeine-containing beverages, including energy drinks has led to a doubling of caffeine-related emergency department visits from 2007-2011.9 The increase in ED visits in association with cardiovascular and other adverse events has been labeled a “rising public health problem in the US” and has led the Food and Drug Administration to investigate the cardiovascular safety of high caffeine content beverages.10 Importantly, the adverse effects of caffeine intake are not limited to the cardiovascular system but also produce significant sleep disruptive effects, particularly when taken later in the day or when multiple doses are utilized.11 One recent population-based study of 18- to 58-year-olds (mean age = 28.5 years of age) estimated that 90% of individuals consume caffeine in the afternoon (12:00-18:00) and 68.5% of people consume caffeine in the evening (18:00-00:00).12

Caffeine content in beverages and foods is increasing in terms of dose and availability, with recent estimates of total daily caffeine consumption suggesting that the average person consumes 319.32 ± 180.94 mg of caffeine per day.12 Information on the sleep-disrupting effects of high doses of caffeine taken in the afternoon and early evening is important, given the increasingly popular use of caffeinated energy drinks and the high caffeine content of premium coffee.13 Such investigations are also critical due to increased caffeine use in younger age groups, where chronic sleep restriction is also increasingly common.8,14,15 Indeed, recent data show that in younger samples, 37% report first use of caffeine during the day at 17:00 or later.16

BRIEF SUMMARY

Current Knowledge/Study Rationale: Despite widespread but often disparate recommendations to refrain from caffeine intake close to bedtime, no studies have investigated the effects of a given dose of caffeine taken at different times before sleep. Understanding the temporal effects of caffeine on sleep are important given the increased utilization of caffeine, and need for empirical data to support specific sleep hygiene recommendations regarding caffeine.

Study Impact: This study demonstrates caffeine consumption even 6 hours before bedtime can have important disruptive effects on both objective and subjective measure of sleep. These findings provide empirical support for sleep hygiene recommendations to refrain from substantial caffeine use for a minimum of 6 hours prior to bedtime.

The sleep disruptive effects of caffeine administration at bedtime are well documented.17 Indeed, caffeine administration has been used as a model of insomnia.18 Dose-response studies demonstrate that increasing doses of caffeine administered at or near bedtime are associated with significant sleep disturbance.19–21 One of the most common recommendations for appropriate sleep hygiene practices is to avoid caffeine close to bedtime. However, evidence is less clear regarding the consumption of caffeine

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Prescription Drug Information, Interactions & Side Effects

Posted today in New Drug Approvals

AstraZeneca’s Imfinzi (durvalumab) has been approved in the US as a 1st-line treatment for adult patients with extensive-stage small cell lung cancer (ES-SCLC) in combination with standard-of-care (SoC) chemotherapies, etoposide plus either carboplatin or cisplatin (platinum-etoposide).
The approval by the Food and Drug Administration…

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Thousands of elective and semi-elective surgeries — including heart and chest operations — are on hold due to the coronavirus pandemic.
If your heart or chest surgery has been postponed, Dr. Robbin Cohen and Dr. Elizabeth David of the Society of Thoracic Surgeons offer some advice.
“We especially don’t want to turn postponed elective or semi-elective…

Posted 3 days ago in New Drug Approvals

 Rockwell Medical, Inc. (NASDAQ:RMTI) (“Rockwell Medical” or the “Company”), a biopharmaceutical company dedicated to transforming anemia management and improving outcomes for patients around the world, today announced that the U.S. Food and Drug Administration (“FDA”) has approved its New Drug…

Posted today in News for Health Professionals

Sarclisa Approved to Treat Patients with Advancing Multiple Myeloma
Multiple myeloma is an incurable blood cancer that forms in the bone marrow. This month, the U.S. Food and Drug Administration (FDA) approved Sanofi’s Sarclisa (isatuximab-irfc) used in combination with pomalidomide and dexamethasone (pom-dex) for the treatment of adults with…

Posted today in Medical

Here are some of the latest health and medical news developments, compiled by the editors of HealthDay:
Eilish, Carey, Other Stars Perform From Home in Coronavirus Benefit Concert
In an hour-long benefit concert to raise money for people affected by the coronavirus pandemic, musicians including Mariah Carey, Billie Eilish, Alicia Keys and Dave Grohl…

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As U.S. coronavirus cases surged past 163,000 on Tuesday, Americans were told they may soon get a look at the statistical disease models that public officials have been using to urge more than 250 million people to stay at home.
The U.S. coronavirus death toll also edged past 3,000, close to surpassing China’s death count of 3,305, the New York Times…

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A simple blood test for dozens of cancers is in the works.
Researchers say their test can detect more than 50 kinds of cancer at early stages and pinpoint their location in the body.
“If these findings are validated, it will be feasible to consider how this test might be incorporated into a broader cancer screening strategy,” said lead researcher…

Posted today in Medical

Could long hours at the office put you at risk for hypothyroidism?
New research suggests it’s possible: Hypothyroidism (an underactive thyroid) was more than twice as common in adults who worked 53 to 83 hours a week as in those who worked 36 to 42 hours a week (3.5% vs. 1.4%).
Hypothyroidism can cause tiredness, depression, feeling cold and weight…

Posted today in Medical

Folks with clogged arteries do as well with medication and lifestyle changes as they do after undergoing invasive procedures to reopen their blood vessels, a major new clinical trial reports.
Bypass

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Facet Effects And Signs Of Taking Too Many Vitamins

Similar to ladies, men have their very own special dietary needs and health issues, especially as they age. A significant programme of funding in health infrastructure will likely be guided by a recognition that that the most effective health outcomes may be achieved by reorienting our health companies in direction of main and neighborhood care where people’s health wants can for probably the most part be met locally, with top quality acute and emergency care offered in the applicable acute hospital settings.

Purple wine can actually improve the body’s production of nitric oxide, which helps blood vessels to expand and circulation to be increased. Biomedical: all facets of health, physical and mental, developed within the human body as influenced by genetic make-up.

A symptom of low blood strain and internal bleeding is a manifestation of ruptured spleen which requires a direct medical attention as it’s potentially life-threatening. “Health: What does good health really mean?.” Medical Information At the moment. Optimistic health influences range from selling healthy diets to organizing high quality family time together.

Moreover iron is considered a healthy food additive by the and Drug Administration. L-arginine works by creating the natural chemicals required to permit blood vessels to calm down and open up. Which means more blood can circulate by way of the penis. Advantages: Vitamin D is crucial for our physique to soak up calcium.

Shea butter softens the pores and skin and promotes healing, leaving the penis easy, supple, and healthy wanting. Carvacrol in oregano oil regenerates the liver cells which is the major detoxing organ within the physique and helps in stopping cancer.

Take advantage of the excessive nutritional content of banana peels to boost your backyard soil, in an inexpensive, pure and efficient approach. And the oxygenation of the physique contains these smaller blood vessels, similar to those who fill the penis. It is caused by a sure kind of bacteria that infected other a part of the body transmitted to the heart by the bloodstream contaminated with the micro organism.…

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