Summit, Colorado Center for Personalized Medicine to Develop Saliva Tests for COVID, Head & Neck Cancer

AURORA, Colo., Oct. 14, 2020 /PRNewswire/ — Summit Biolabs, Inc., an early-stage molecular diagnostics company specializing in saliva-based testing for COVID-19 and head & neck cancer, and the Colorado Center for Personalized Medicine (CCPM) at the University of Colorado Anschutz Medical Campus announced today a broad strategic collaboration involving research, development and commercialization of saliva liquid-biopsy tests for early cancer detection and diagnosis of COVID-19 and other viral contagions.

The CCPM holds one of the largest research biobanks in the United States with clinical data from more than 8.7 million de-identified patient records and plans to integrate the data with personalized genomic information.

“This partnership brings two innovative programs together to optimize COVID testing at a time when it’s desperately needed,” says Kathleen Barnes, Ph.D., Professor and Director of CCPM at the University of Colorado Anschutz Medical Campus. “Collaborations like this are crucial in moving research forward and advancing and expanding clinical testing to as many members of our community as possible. Working with Summit Biolabs, and leveraging technology developed by our colleagues here at the Anschutz Medical Campus, will help us achieve these goals and establish a non-invasive testing process that will benefit patients in Colorado and beyond.”

Summit Biolabs is developing breakthrough tests to improve the detection of COVID-19 and to advance the early detection of human cancers, including head & neck cancer, using simple, non-invasive saliva liquid-biopsy technology developed by Dr. Shi-Long Lu and colleagues at the University of Colorado Anschutz Medical Campus. Head & neck cancer has been scientifically overlooked, yet is medically important. Summit Biolabs’ research foundation and competency in head & neck cancer diagnosis enabled the company’s pivot to saliva-based testing for coronavirus, COVID-19.

“We are excited to collaborate with CCPM to develop and commercialize Summit Biolabs’ portfolio of developmental saliva or non-blood liquid-biopsy tests.” said Bob Blomquist, Chief Executive Officer at Summit Biolabs. “This collaboration broadens and strengthens Summit Biolabs’ ability to bring to market life-changing saliva liquid-biopsy tests that ultimately enable better treatment and improved outcomes for patients.”

About Summit Biolabs

Summit Biolabs is harnessing the power of saliva-based diagnostics to address critical challenges in COVID-19 and head & neck cancer testing. Founded on the discoveries of Dr. Shi-Long Lu, Associate Professor of Otolaryngology, Summit Biolabs is being spun out from the University of Colorado Anschutz Medical Campus.

Summit Biolabs is pioneering early detection of head & neck cancer recurrence using a first of its kind saliva liquid-biopsy test, HNKlear. HNKlear is a proprietary, non-invasive saliva test that provides more effective, more accurate, and earlier detection of head and neck cancer recurrence than traditional diagnostic methods. Summit Biolabs is leveraging its core competencies in saliva-based molecular diagnostics and viral nucleic acid testing (i.e., oral oncogenic human papillomavirus detection) to diagnose COVID-19. Along with our clinical and laboratory partners, Summit Biolabs is developing the first comprehensive panel of highly-accurate saliva-based tests for COVID-19 infection, quantitation, and immune response. Summit Biolabs is headquartered in Aurora, Colorado.

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Colorado sees surge in coronavirus cases

DENVER — Colorado is experiencing another surge of coronavirus cases and hospitalizations, prompting Gov. Jared Polis to plead Tuesday with residents to wear masks, stay home as much as possible, and maintain social distancing practices.

As of Tuesday, Colorado’s three-day average positivity rate — the percentage of total tests coming in positive — was 5.4%, and the state recorded 1,000 new cases both on Saturday and on Monday, the highest daily numbers recorded during the pandemic, Polis said.

About 290 people were hospitalized for COVID-19 on Tuesday, the highest total since May 31, The Denver Post reported.


During a briefing on the pandemic, Polis didn’t suggest he was contemplating renewed mandatory restrictions on business or other activities to stem the surge. But he insisted: “If this continues, our hospital capacity will be in jeopardy.”

The World Health Organization recommends trying to keep the positivity rate below 5% of all tests. Higher rates suggest authorities are missing large numbers of infections.

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HERE’S WHAT YOU NEED TO KNOW ABOUT THE VIRUS OUTBREAK:

— WHO: Europe reported more than 700,000 coronavirus cases last week

— Dutch order bars, restaurants closed over coronavirus concerns

— India has 55,342 coronavirus cases, lowest single-day tally since mid-August

— Safety monitoring panel will try to determine what might have caused sickness in a second COVID-19 vaccine trial paused over unexplained illness

— New poll finds coronavirus pandemic has thrust many Americans into role of caring for an older or disabled loved one for first time.

— Cristiano Ronaldo latest high-profile soccer player infected with the coronavirus, Portuguese soccer federation says.

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— Follow AP’s pandemic coverage at http://apnews.com/VirusOutbreak and https://apnews.com/UnderstandingtheOutbreak

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HERE’S WHAT ELSE IS HAPPENING:

SIOUX FALLS, S.D. — Gov. Kristi Noem has blamed South Dakota’s recent surge in coronavirus cases on an increase in testing, even as the state sees a new high in the number of people hospitalized by the virus.

There are currently no open general-care hospital beds in the southeastern part of the state, which contains the two largest hospitals, according to the Department of Health. Hospitals are dealing with both an increase in COVID-19 patients and people needing other medical care. The Sioux Falls hospitals do have about 41% of their Intensive Care Units available.

“We have triple the amount of testing that we are doing in the state of South Dakota, which is why we’re seeing elevated positive cases,” Noem said. “That’s normal, that’s natural, that’s expected.”

The Department of Health reports 302 COVID-19 patients are hospitalized — an all-time high in the state.

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DES MOINES, Iowa — Hospitalizations, virus spread and deaths continued at high levels Tuesday in Iowa on the eve of a campaign rally by President Donald Trump, where Gov. Kim Reynolds and thousands of other Trump supporters will likely defy the governor’s own emergency proclamation to keep distance between people in public places.

A public health emergency proclamation signed by Reynolds requires that organizers of mass gatherings “must ensure at least six feet of

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